95306-88-0Relevant academic research and scientific papers
Design and synthesis of the first indole-based blockers of Panx-1 channel
Crocetti, Letizia,Guerrini, Gabriella,Puglioli, Sara,Giovannoni, Maria Paola,Di Cesare Mannelli, Lorenzo,Lucarini, Elena,Ghelardini, Carla,Wang, Junjie,Dahl, Gerhard
, (2021)
Panx-1 is a membrane channel protein involved in some pathologies such as ischemic stroke, cancer and neuropathic pain, thus representing a promising therapeutic target. We present here a study aimed at obtaining the first class of selective Panx-1 blocke
