953079-61-3

Upstream product

• 70-11-1 α-bromoacetophenone 
• 27038-81-9 8-(hydroxymethyl)-3-methyl-3,7-dihydro-1H-purine-2,6-dione 

Downstream Products

• 1416209-36-3 2-({[3-methyl-2,6-dioxo-7-(2-oxo-2-phenylethyl)-2,3,6,7-tetrahydro-1H-purin-8-yl]methyl}thio)-5,6,7,8,9,10-hexahydrocycloocta[b]pyridine-3-carbonitrile 
• 1416209-37-4 4-(2-chlorophenyl)-2-({[3-methyl-2,6-dioxo-7-(2-oxo-2-phenylethyl)-2,3,6,7-tetrahydro-1H-purin-8-yl]methyl}thio)-5,6,7,8-tetrahydroquinoline-3-carbonitrile 
• 1416209-38-5 1-methyl-3-({[3-methyl-2,6-dioxo-7-(2-oxo-2-phenylethyl)-2,3,6,7-tetrahydro-1H-purin-8-yl]methyl}thio)-5,6,7,8-tetrahydroisoquinoline-4-carbonitrile 
• 1416209-40-9 1-methyl-3-({[3-methyl-2,6-dioxo-7-(2-oxo-2-phenylethyl)-2,3,6,7-tetrahydro-1H-purin-8-yl]methyl}-thio)-6,7-dihydro-5H-cyclopenta[c]pyridine-4-carbonitrile 
• 1416209-42-1 6-tert-butyl-2-({[3-methyl-2,6-dioxo-7-(2-oxo-2-phenylethyl)-2,3,6,7-tetrahydro-1H-purin-8-yl]methyl}thio)-5,6,7,8-tetrahydroquinoline-3-carbonitrile 
• 1416209-43-2 4,6-dimethyl-2-({[3-methyl-2,6-dioxo-7-(2-oxo-2-phenylethyl)-2,3,6,7-tetrahydro-1H-purin-8-yl]methyl}thio)nicotinonitrile 
• 1416209-44-3 4-(4-chlorophenyl)-2-({[3-methyl-2,6-dioxo-7-(2-oxo-2-phenylethyl)-2,3,6,7-tetrahydro-1H-purin-8-yl]methyl}thio)-5,6,7,8-tetrahydroquinoline-3-carbonitrile 
• 1416209-45-4 2-({[3-methyl-2,6-dioxo-7-(2-oxo-2-phenylethyl)-2,3,6,7-tetrahydro-1H-purin-8-yl]methyl}thio)-4,6-diphenylnicotinonitrile 
• 1170005-16-9 C₁₅H₁₃ClN₄O₃ 
• 1416209-46-5 1-methyl-7-phenyl-10,11,12,13,14,15-hexahydro-1H-cycloocta[5'',6'']pyrido[3'',2'':4',5']thieno-[3',2':5,6][1,4]diazepino[7,1-f]purine-2,4(3H,6H)-dione 
• 1416209-47-6 9-(2-chlorophenyl)-1-methyl-7-phenyl-10,11,12,13-tetrahydro-1H-purino[7'',8'':1',7'][1,4]diazepino-[5',6':4,5]thieno[2,3-b]quinoline-2,4(3H,6H)-dione 
• 1416209-48-7 2,14-dimethyl-8-phenyl-3,4,5,6-tetrahydro-9H-purino[7'',8'':1',7'][1,4]diazepino[5',6':4,5]thieno-[2,3-c]isoquinoline-11,13(12H,14H)-dione 
• 1416209-52-3 C₂₉H₂₈N₆O₂S 
• 1416209-53-4 1,9,11-trimethyl-7-phenyl-1H-pyrido[3'',2'':4',5']thieno[3',2':5,6][1,4]diazepino[7,1-f]purine-2,4(3H,6H)-dione 

Relevant academic research and scientific papers

Condensed sulfur-containing pyridine systems 3.*Construction of penta- and hexacyclic heterocyclic systems by the cascade reaction of 3-cyanopyridine-2(1H)-thiones and 3-cyano-pyridine-2(1H)-thiolates with 8-chloromethyl-3-methyl-7-(2-oxo-2-phenylethyl)xanthene

The alkylation of 3-cyanopyridine-2(1H)-thiones with 8-chloromethyl-3- methyl-7-(2-oxo-2-phenylethyl)- xanthene in a KOH-H2O-DMF system upon heating leads to the formation of pyrido-[3″,2″:4′,5′] thieno[3′,2′:5,6][1,4]diazepino[7,1-f]purine-2,4(3H,6H)-dione derivatives in good yields. Under milder conditions, the intermediates of the cascade reactions, namely, 2-({[3-methyl-2,6-dioxo-7-(2-oxo-2-phenylethyl)-2,3, 6,7-tetrahydro-1H-purin-8-yl]methyl}thio)pyridine-3-carbonitriles, can be isolated and characterized.