95312-27-9Relevant articles and documents
EPOXYKETONE COMPOUNDS FOR ENZYME INHIBITION
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Paragraph 0097; 0098, (2016/02/26)
The present disclosure relates to novel compounds and pharmaceutical compositions thereof which are useful as inhibitors of proteasomes. The compounds provided herein have improved proteasome potency and selectivity, and increased aqueous solubility, and
Compounds for enzyme inhibition
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Page/Page column 23; 24, (2008/06/13)
Peptide-based compounds including heteroatom-containing, three-membered rings efficiently and selectively inhibit specific activities of N-terminal nucleophile (Ntn) hydrolases associated with the proteasome. The peptide-based compounds include an epoxide