95337-74-9

Usage

Uses

Used in Organic Synthesis:
2-Pyridinamine,6-butyl-(9CI) is used as a building block in organic synthesis for the preparation of various pharmaceuticals, agrochemicals, and other fine chemicals. Its unique structure and functional groups make it a valuable component in the development of new compounds with specific therapeutic or chemical properties.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, 2-Pyridinamine,6-butyl-(9CI) is used as an intermediate in the synthesis of drugs with potential therapeutic applications. Its presence in the molecular structure of these drugs can contribute to their biological activity and pharmacological properties, making it an essential component in drug discovery and development.
Used in Agrochemical Industry:
2-Pyridinamine,6-butyl-(9CI) is also utilized in the agrochemical industry for the synthesis of compounds with pesticidal or herbicidal properties. Its incorporation into these agrochemicals can enhance their effectiveness in controlling pests and weeds, thereby contributing to increased crop yields and agricultural productivity.
Used in Drug Discovery:
2-Pyridinamine,6-butyl-(9CI) has been studied for its potential biological and pharmacological activities, including its antifungal and antibacterial properties. Researchers are exploring its use in drug discovery to develop new therapeutic agents that can combat various infections and diseases.

InChI:InChI=1/C9H14N2/c1-2-3-5-8-6-4-7-9(10)11-8/h4,6-7H,2-3,5H2,1H3,(H2,10,11)

Upstream product

• 95337-75-0 6-Butyl-2-(2,5-dimethyl-1H-pyrrol-1-yl)pyridine 
• 1309921-19-4 2-bromo-6-butylpyridine 
• 1309921-20-7 N-(6-butylpyridin-2-yl)acetamide 
• 32570-89-1 2-(2,5-dimethyl-1H-pyrrol-1-yl)-6-methylpyridine 
• 1824-81-3 2-Amino-6-methylpyridine 

Downstream Products

• 1309921-02-5 3-cyano-5-fluoro-N-(6-butylpyridin-2-yl)benzamide 

Relevant academic research and scientific papers

Design and synthesis of substituted N-(1,3-diphenyl-1H-pyrazol-5-yl) benzamides as positive allosteric modulators of the metabotropic glutamate receptor subtype 5

Based on SAR in the alkyne class of mGlu5 receptor negative allosteric modulators and a set of amide-based positive allosteric modulators, optimized substitution of the aryl bring was used to create substituted N-(1,3-diphenyl-1H-pyrazol-5-yl)benzamides.

Bisaryl-sulfonamides

Compounds, compositions and methods are provided that are useful in the treatment or prevention of a condition or disorder mediated by PPARγ or PPARδ. In particular, the compounds of the invention modulate the function of PPARγ or PPARδ. The subject methods are particularly useful in the treatment and/or prevention of diabetes, obesity, hypercholesterolemia, rheumatoid arthritis and atherosclerosis.

Protection of Primary Amines as N-Substituted 2,5-Dimethylpyrroles

Protection of primary amine group is achieved by incorporating it into an N-substituted 2,5-dimethylpyrrole system.The method affords protection against strong bases and nucleophiles, heating with concentrated alkali, standard mineral acid work-up conditions, and various other reagents.Phenyl-, pyridil-, thiazolyl-, and alkyl-amines have been studied.All give trisubstituted pyrroles in high yield (>80percent) by reaction with hexane-2,5-dione.The pyrroles from the first three types are stable to storage; even the N-alkyl compounds can be used without difficulty.Regeneration of the amine group, by treatment with hydrxylamine hydrochloride, is efficient (80percent yield) with the phenyl, pyridyl, and alkyl compounds but less satisfactory (60 - 65percent generally but down to 25percent in two cases) with the thiazolyl derivatives.