95356-15-3 Usage
General Description
1-(O-Tolyl)piperazine hydrochloride is a chemical compound that belongs to the category of piperazine derivatives. It is used in the pharmaceutical industry as a building block for the synthesis of various pharmaceutical drugs. 1-(O-TOLYL)PIPERAZINE HYDROCHLORIDE is commonly used in the preparation of antihistamines and antipsychotics. It acts as a central nervous system stimulant and has been studied for its potential as a psychoactive substance. The hydrochloride salt form of 1-(O-Tolyl)piperazine is water-soluble and stable, making it suitable for use in pharmaceutical formulations. This chemical is regulated and should be handled with care due to its potential health hazards if not used appropriately.
Check Digit Verification of cas no
The CAS Registry Mumber 95356-15-3 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 9,5,3,5 and 6 respectively; the second part has 2 digits, 1 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 95356-15:
(7*9)+(6*5)+(5*3)+(4*5)+(3*6)+(2*1)+(1*5)=153
153 % 10 = 3
So 95356-15-3 is a valid CAS Registry Number.
95356-15-3Relevant articles and documents
Design, synthesis, and biological evaluation of structurally constrained hybrid analogues containing ropinirole moiety as a novel class of potent and selective dopamine D3 receptor ligands
Zhou, Benhua,Hong, Kwon Ho,Ji, Min,Cai, Jin
, p. 1597 - 1609 (2018/07/31)
Two series of hybrid analogues were designed, synthesized, and evaluated as a novel class of selective ligands for the dopamine D3 receptor. Binding affinities of target compounds were determined (using the method of radioligand binding assay). Compared to comparator agent BP897, compounds 2a and 2c were found to demonstrate a considerable binding affinity and selectivity for D3 receptor, and especially compound 2h was similarly potent and more selective D3R ligand than BP897, a positive reference. Thus, they may provide valuable information for the discovery and development of highly potent dopamine D3 receptor ligands with outstanding selectivity.