953776-41-5Relevant academic research and scientific papers
Mixed unsymmetric oxadiazoline and/or imine platinum(ii) complexes
Lasri, Jamal,Adilia Januario Charmier,Da Silva, M. Fatima C. Guedes,Pombeiro, Armando J. L.
, p. 3259 - 3266 (2008/02/10)
Iminoacylation of acetone oxime Me2CNOH 2 upon reaction with trans-[PtCl2(NCCH2CO2Me)2] 1 and [2 + 3] cycloaddition of acyclic nitrone -O+N(Me)C(H)(C 6H4Me-4) 3 to a nitrile ligand in 1 lead to the formation of mono-imine trans-[PtCl2(imine-a)(NCCH2CO 2Me)] 4 [imine-a = NHC(CH2CO2Me)ONCMe 2] and mono-oxadiazoline trans-[PtCl2(oxadiazoline-a) (NCCH2CO2Me)] 6 [oxadiazoline-a = NC(CH2CO 2Me)ON(Me)C(H)(C6H4Me-4)] unsymmetric mixed ligand complexes, respectively, as the main products. Reactions of 6 or 4 with acetone oxime 2, cyclic nitrone -O+NCHCH 2CH2CMe2 8 or N,N-diethylhydroxylamine 11 give access, in moderate to good yields, to the unsymmetric mixed ligand oxadiazoline and/or imine complexes trans-[PtCl2(oxadiazoline-a)(imine-a)] 9, trans-[PtCl2(oxadiazoline-a)(oxadiazoline-b)] 10 [oxadiazoline-b = NC(CH2CO2Me)ONC(H)CH2CH2CMe 2], trans-[PtCl2(imine-a)(imine-b)] 12 [imine-b = NHC(CH2CO2Me)ONEt2] or trans-[PtCl 2(imine-a)(oxadiazoline-b)] 13. The cis mono-imine mixed ligand complex cis-[PtCl2(imine-a)(NCCH2CO2Me)] 4a is the major product from the reaction of cis-[PtCl2(NCCH 2CO2Me)2] 1a with the oxime 2, while the di-imine compound cis-[PtCl2(imine-a)2] 5a is a minor product. Reaction of cis-[PtCl2(imine-a)(NCCH2CO 2Me)] 4a with N,N-diethylhydroxylamine 11 or the cyclic nitrone 8 affords, in good yields, the unsymmetric mixed ligand complexes cis-[PtCl 2(imine-a)(imine-b)] 12a or cis-[PtCl2(imine-a) (oxadiazoline-b)] 13a, respectively. All these complexes were characterized by elemental analyses, IR and 1H, 13C and 195Pt NMR spectroscopies, and FAB+-MS. The X-ray structural analysis of trans-[PtCl2{NHC(CH2CO2Me)ONCMe 2}(NCCH2CO2Me)] 4 is also reported. The Royal Society of Chemistry.
