95384-35-3

Upstream product

• 95102-10-6 3-[(5-benzyloxycarbonylamino-1-methoxycarbonyl)pentyl-(1S)-amino]-1-ethoxycarbonylmethyl-2,3,4,5-tetrahydro-1H-[1](3S)-benzazepin-2-one 
• 97878-34-7 (S)-6-Benzyloxycarbonylamino-2-[1-ethoxycarbonylmethyl-2-oxo-1,2,4,5-tetrahydro-benzo[b]azepin-(3E)-ylideneamino]-hexanoic acid methyl ester 
• 88372-49-0 1-ethoxycarbonylmethyl-2,3,4,5-tetrahydro-1H-[1]benzazepine-2,3-dione 
• 94793-89-2 3-(S)-amino-1-ethoxycarbonylmethyl-2,3,4,5-tetrahydro-1H-[1]benzazepine-2-one 
• 24498-31-5 (S)-methyl 2-amino-6-(benzyloxycarbonylamino)hexanoate 

Downstream Products

• 97878-35-8 3(S)-<<(1S)-5-amino-1-carboxypentyl>amino>-2,3,4,5-tetrahydro-2-oxo-1H-1-benzazepine-1-ethanoic acid 

Relevant academic research and scientific papers

3-Amino-[1]-benzazepin-2-one-1-alkanoic acids

Variously substituted 1-carboxymethyl-3-(carboxymethylamino)-2,3,4,5-tetrahydro-1H-[1]benzazepin-2-ones and functional derivatives are angiotensin converting enzyme inhibitors and are useful as antihypertensive agents. Synthesis of, compositions and methods of treatment utilizing such compounds are included.

Angiotensin Converting Enzyme Inhibitors: Structure-Activity Profile of 1-Benzazepin-2-one Derivatives

The preparation of a series of 3-amino-2-oxo-2,3,4,5-tetrahydro-1H-1-benzazepine-1-acetic acid derivatives 5a-y by reductive amination of 2,3,4,5-tetrahydro-1H-1-benzazepine-2,3-dione (7) with L-amino acid derivatives is described.The compounds were teste