95395-34-9

Upstream product

• 68236-25-9 2-chloro-5,6,7-trimethoxyquinoline-3-carboxaldehyde 
• 95395-22-5 5,6,7-trimethoxyquinoline-3-carboxaldehyde 
• 142-04-1 aniline hydrochloride 
• 95395-28-1 (Z)-3-Morpholin-4-yl-2-(5,6,7-trimethoxy-quinolin-3-ylmethyl)-acrylonitrile 

Relevant academic research and scientific papers

Synthesis and in vitro antibacterial activity of some 2,4-diamino-5-(3-quinolinylmethyl) pyrimidines

The synthesis and the in vitro antibacterial activity of six new 2,4-diamino-5-(3-quinolinylmethyl)pyrimidine analogous to trimethoprim (TMP) are described. The most active compound, 2,4-diamino-5-[(5,6,7-trimethoxy-3-quinolinyl)methyl]pyrimidine showed a remarkable in vitro synergism with sulfamethoxazole (SMZ) against Gram-positive and Gram-negative bacteria.