95406-76-1Relevant academic research and scientific papers
NOVEL IMIDAZOLE COMPOUND AND USE THEREOF AS MELANOCORTIN RECEPTOR AGONIST
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Paragraph 0542, (2018/10/04)
The present invention relates to a novel imidazole compound or a pharmaceutically acceptable salt thereof having a melanocortin receptor agonistic activity, and medical use thereof. The present invention relates to an imidazole compound represented by general formula [I] [wherein: Ring A represents an optionally substituted aryl group or the like; R1 represents a hydrogen atom, an optionally substituted alkyl group, or the like; R2 represents a hydrogen atom, a halogen atom, or the like; and R3 represents an optionally substituted alkyl group] or a pharmaceutically acceptable salt thereof.
Pharmaceutical compositions (by machine translation)
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Paragraph 0204, (2019/01/31)
[Problem] imidazole compound or its pharmacologically acceptable salt in the melanocortin receptor activity that operates as an active ingredient of a pharmaceutical composition comprising. "I" general formula [a]" Formula, the aryl group may be substituted A ring represents a; R1 Represents a hydrogen atom, or an alkyl group which may be substituted represented; R2 Represents a hydrogen atom, a halogen atom or represents a; R3 The alkyl group may be substituted " represented by the imidazole compound, its pharmacologically acceptable salt as an active ingredient in a pharmaceutical composition. [Drawing] no (by machine translation)
Ibotenic Acid Analogues. Synthesis, Molecular Flexibility, and in Vitro Activity of Agonists and Antagonists at Central Glutamic Acid Receptors
Lauridsen, Joern,Honore, Tage,Krogsgaard-Larsen, Povl
, p. 668 - 672 (2007/10/02)
The syntheses of (RS)-α-amino-3-hydroxy-5-tert-butyl-4-isoxazolepropionic acid (9, ATPA), (α-RS,β-RS)-α-amino-β-methyl-3-hydroxy-5-isoxazolepropionic acid (8), (RS)-α-amino-3-hydroxy-5-isoxazolebutyric acid (15a), and (RS)-α-amino-3-hydroxy-5-isoxazoleval
