954096-32-3Relevant academic research and scientific papers
Construction of the taxane skeleton via the stereoselective conjugate addition of cyanide and the intramolecular B-alkyl Suzuki-Miyaura coupling reaction
Utsugi, Masayuki,Kamada, Yasuaki,Miyamoto, Hidetoshi,Nakada, Masahisa
, p. 6868 - 6872 (2007)
Construction of the taxane skeleton via the stereoselective conjugate addition of cyanide and the intramolecular B-alkyl Suzuki-Miyaura coupling reaction is described. A conjugate addition of cyanide to enone 17 proceeded diastereoselectively to provide t
Development of silicon-tethered anionic reaction and its application to the synthesis of chiral A-ring moieties of Taxol
Iwamoto, Mitsuhiro,Miyano, Masayuki,Utsugi, Masayuki,Kawada, Hatsuo,Nakada, Masahisa
, p. 8647 - 8651 (2007/10/03)
Silicon-tethered intramolecular nucleophilic additions of a hydroxymethyl unit to ketones in β-hydroxyketones have been developed. The product obtained by this protocol was successfully converted to chiral A-ring moieties of Taxol. Also developed was a pr
