954112-83-5 Usage
Chemical structure
Pyrrolopyridine derivative It is derived from a pyrrole and a pyridine ring fused together.
Carbonitrile group
Present The compound contains a cyano group (C≡N) which may impart specific chemical and biological properties.
Chlorine atom
Located at the 5-position of the pyridine ring The presence of chlorine enhances the reactivity and properties of the compound.
2-Methyl group
Present A methyl group (CH3) is attached to the 2-position of the pyrrolopyridine core, which may influence its reactivity and properties.
Potential applications
Pharmaceutical and agrochemical industries The compound's structural features make it suitable for use as a building block in the synthesis of biologically active molecules.
Use as a building block
Synthesis of various biologically active molecules The compound can be used to create new drugs and agrochemicals due to its unique structure.
Valuable intermediate
Development of new drugs and agrochemicals The presence of cyano and chloro groups makes it a useful intermediate for creating new compounds with specific chemical and biological properties.
Check Digit Verification of cas no
The CAS Registry Mumber 954112-83-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 9,5,4,1,1 and 2 respectively; the second part has 2 digits, 8 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 954112-83:
(8*9)+(7*5)+(6*4)+(5*1)+(4*1)+(3*2)+(2*8)+(1*3)=165
165 % 10 = 5
So 954112-83-5 is a valid CAS Registry Number.
954112-83-5Relevant academic research and scientific papers
Bahekar, Rajesh H.,Jain, Mukul R.,Jadav, Pradip A.,Prajapati, Vijay M.,Patel, Dipam N.,Gupta, Arun A.,Sharma, Ajay,Tom, Robby,Bandyopadhya, Debdutta,Modi, Honey,Patel, Pankaj R.
, p. 6782 - 6795 (2007)
In the present investigation, two series of 2,5-disubstituted-3-imidazol-2-yl-pyrrolo[2,3-b]pyridines (2a-l) and thieno[2,3-b]pyridines (3a-l) were designed as analogs of BL 11282 (1). The in vitro glucose dependent insulinotropic activity of all the test compounds was evaluated using RIN5F cell based assay and all the test compounds showed glucose and concentration dependent insulin secretion. The in vivo antidiabetic activities of most potent compounds from each series (2c and 3c) were assessed in C57BL/6J mice. Compounds 2c and 3c showed dose dependent insulin secretion and significant glucose reduction in vivo. In general, compounds 2c and 3c were found to be equipotent at all the three different doses selected and with respect to BL 11282, both the test compounds were found to be more potent, at all the time points.
