954142-48-4

Upstream product

• 17261-28-8 ortho-diphenylphosphinobenzoic acid 
• 130532-54-6 (S)-((1E)-3-hydroxy-propenyl)-2,2-dimethyl-oxazolidine-3-carboxylic acid tert-butyl ester 
• 95715-87-0 (R)-3-tert-butoxycarbonyl-4-formyl-2,2-dimethyloxazolidine 
• 129483-65-4 (4S)-1,1-Dimethylethyl 4-<(E)-3'-methoxy-3'-oxo-1'-propenyl>-2,2-dimethyl-3-oxazolidinecarboxylate 

Downstream Products

• 1258005-22-9 tert-butyl (4S)-4-[(1E)-3-{[2-(diphenylphosphoryl)benzoyl]oxy}prop-1-enyl]-2,2-dimethyl-1,3-oxazolidine-3-carboxylate 

Relevant academic research and scientific papers

1,2-diastereoselective C-C bond-forming reactions for the synthesis of chiral β-branched α-amino acids

SN2′ sequences have been employed for the synthesis of β-branched α-amino acids using 1,2-diastereocontrol for forming C-C bonds. An oxazolidine fragment derived from Garner's aldehyde provides the handle for facial discrimination and acts as a

A new method for the synthesis of chiral β-branched α-amino acids

A new method for the synthesis of chiral β-branched α-amino acids based on a copper-mediated directed allylic substitution reaction with Grignard reagents is reported. This is the first case in which a δ-stereogenic center is controlling the diastereosele