954232-01-0Relevant academic research and scientific papers
Synthesis and biological evaluation of quinoxaline derivatives as tubulin polymerization inhibitors that elevate intracellular ROS and triggers apoptosis via mitochondrial pathway
Qi, Jianguo,Huang, Jing,Zhou, Xiaomin,Luo, Wen,Xie, Jiaxin,Niu, Linqiang,Yan, Zhijie,Luo, Yang,Men, Yuhui,Chen, Yanan,Zhang, Yahong,Wang, Jianhong
, p. 617 - 627 (2019/01/18)
A series of novel quinoxaline derivatives were synthesized and evaluated for their antiproliferative activity in three human cancer cell lines. Compound 12 exhibited the most potent antiproliferative activity with IC50 in the range of 0.19–0.51
NOVEL COMPOUNDS
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Page/Page column 59, (2009/08/14)
The invention relates to novel benzimidazole compounds of formula (I) wherein R1 to R1 are as defined in the specification, pharmaceutically acceptable salts thereof, to pharmaceutical compositions containing them and their use in medicine. In particular, the invention relates to compounds that are agonists of peroxisome proliferators-activated receptorγ (PPARγ).
