954411-08-6Relevant academic research and scientific papers
2-Substituted piperazine-derived imidazole carboxamides as potent and selective CCK1R agonists for the treatment of obesity
Berger, Richard,Zhu, Cheng,Hansen, Alexa R.,Harper, Bart,Chen, Zhesheng,Holt, Tom G.,Hubert, James,Lee, Susan J.,Pan, Jie,Qian, Su,Reitman, Marc L.,Strack, Alison M.,Weingarth, Drew T.,Wolff, Michael,MacNeil, Douglas J.,Weber, Ann E.,Edmondson, Scott D.
body text, p. 4833 - 4837 (2009/06/06)
The discovery and structure-activity relationship of 1,2-diarylimidazole piperazine carboxamides bearing polar side chains as potent and selective cholecystokinin 1 receptor (CCK1R) agonists are described. Optimization of this series resulted in the disco
