95449-69-7Relevant academic research and scientific papers
Spirocyclopropane compounds. IV. Synthesis of 5-acetylspiro[benzofuran-2(3H),1'-cyclopropan]-3-one-related compounds for evaluation as gastric antisecretory and antiulcer agents
Watanabe,Kawada,Hirata,Maki,Imada
, p. 3551 - 3560 (2007/10/02)
5-Acetylspiro[benzofuran-2(3H),1'-cyclopropan]-3-one (1a) shows potent gastric antisecretory and antiulcer activities in rats. In an attempt to improve the pharmacological profile of 1a, we synthesized positional isomers, as well as the prenyloxy and oxim
