954502-32-0

Upstream product

• 444307-99-7 (1R,5S,8S,9S)-2-benzyl-8-(tert-butyldimethylsilyloxymethyl)-6,6-dimethyl-3,7-dioxa-2-azabicyclo[3.3.1]nonan-9-ol 
• 870461-00-0 (1S,5R,8S)-2-benzyl-8-(tert-butyldimethylsilyloxymethyl)-6,6-dimethyl-3,7-dioxa-2-azabicyclo[3.3.1]nonan-9-one 
• 954502-29-5 (2S,3R,4S,5S)-[4-benzyloxy-2-(tert-butyldimethylsiloxymethyl)-5-(hydroxymethyl)-6,6-dimethyltetrahydropyran-3-yl]carbamic acid tert-butyl ester 
• 954502-28-4 (1R,5S,8S,9S)-2-benzyl-9-benzyloxy-8-(tert-butyldimethylsiloxymethyl)-6,6-dimethyl-3,7-dioxa-2-azabicyclo[3.3.1]nonane 
• 954502-31-9 (1S,4S,5R,8S)-8-benzyloxy-4-(tert-butyldimethylsiloxymethyl)-2,2-dimethyl-7-oxo-3-oxa-6-azabicyclo[3.2.1]octane-6-carboxylic acid tert-butyl ester 

Downstream Products

• 954502-31-9 (1S,4S,5R,8S)-8-benzyloxy-4-(tert-butyldimethylsiloxymethyl)-2,2-dimethyl-7-oxo-3-oxa-6-azabicyclo[3.2.1]octane-6-carboxylic acid tert-butyl ester 

Relevant academic research and scientific papers

Enantiopure aminopyrans by a lewis acid promoted rearrangement of 1,2-oxazines: Versatile building blocks for oligosaccharide and sugar amino acid mimetics

1,3-Dioxolanyl-substituted 1,2-oxazines, such as syn-l and anti-1, rearrange under Lewis acidic conditions to provide bicyclic products 2-5. Subsequent reductive transformations afforded enantiopure 3-aminopyran derivatives such as 7 and 9 or their protec

Simple modifications of enantiopure 1,2-oxazines leading to building blocks for carbohydrate and peptide mimetics

Starting from easily available enantiopure pyran derivatives we prepared bicyclic γ-lactam 6, azide 10, and alkyne 18 using simple procedures. These compounds were crucial intermediates for the synthesis of γ-amino acid 8 and dipeptide 9 as well as triazo