95464-10-1

Upstream product

• 7468-48-6 6-deoxy-6-iodotetra-O-acetyl-β-D-glucopyranose 
• 24871-54-3 acetoxy α-D-2,3,4-triacetoxy-6-deoxy-6-iodoglucopyranoside 
• 10225-48-6 1,2,3,4-tetra-O-acetyl-6-bromo-6-deoxy-β-D-glucopyranose 

Downstream Products

• 121965-11-5 1,3-dimethyl-7-[O²,O³,O⁴-triacetyl-O⁶-(bis-benzyloxy-phosphoryl)-β-D-glucopyranosyl]-3,7-dihydro-purine-2,6-dione 

Relevant academic research and scientific papers

COMPARATIVE STABILITY OF 1-ALKOXYALKYL α-D-GLUCOSIDES IN THE PRESENCE OF ACID OR α-D-GLUCOSIDASE FROM YEAST

The aminated 1-alkoxyalkyl glycosides 6-amino-6-deoxy-α-D-glucopyranoside (3) and 6-amino-6-deoxy-α-D-glucopyranoside (4) have been synthesised and characterised.These compounds as well as α-D-glucopyranoside (1) prepared earlier are resistant against α-D-glucosidase (maltase, α-D-glucoside glucohydrolase, E.C. 3.2.1.20) from yeast, yet undergo hydrolysis under relatively mild acidic conditions.The kinetic parameters of the interaction with α-D-glucosidase and with acid were determined.The relative rates of acid hydrolysis of aminated 1-alkoxyalkyl glucosides compared with aminated ordinary glycosides suggest essential differences in the mechanism of acid-catalysed hydrolysis.