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(3R,4R)-rel-4-Fluoro-3-piperidinol hydrochloride is a fluorinated piperidinol derivative with the molecular formula C5H10FNO-HCl. It is a white solid in its hydrochloride salt form, featuring a 3R,4R stereochemistry with two chiral centers at the third and fourth positions of the piperidinol ring. This versatile chemical compound possesses potential pharmacological properties and is valuable in the synthesis of pharmaceutical drugs.

955028-83-8

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955028-83-8 Usage

Uses

Used in Pharmaceutical Industry:
(3R,4R)-rel-4-Fluoro-3-piperidinol hydrochloride is used as an intermediate in the synthesis of pharmaceutical drugs for its potential pharmacological properties. The presence of the hydrochloride salt enhances its bioavailability and makes it easier to handle and store, which is advantageous for various applications in drug development.
Used in Drug Synthesis:
(3R,4R)-rel-4-Fluoro-3-piperidinol hydrochloride is used as a key building block in the creation of new pharmaceutical compounds, leveraging its unique stereochemistry and fluorination to impart specific biological activities and improve drug efficacy.
Used in Medicinal Chemistry Research:
(3R,4R)-rel-4-Fluoro-3-piperidinol hydrochloride is utilized as a research tool in medicinal chemistry to explore the structure-activity relationships of piperidinol derivatives and to develop novel therapeutic agents with improved pharmacokinetic and pharmacodynamic profiles.
Used in Chiral Compounds Development:
(3R,4R)-rel-4-Fluoro-3-piperidinol hydrochloride is employed as a chiral compound in the development of enantiomerically pure drugs, taking advantage of its defined stereochemistry to ensure the desired biological activity and minimize potential side effects associated with the less active enantiomer.

Check Digit Verification of cas no

The CAS Registry Mumber 955028-83-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 9,5,5,0,2 and 8 respectively; the second part has 2 digits, 8 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 955028-83:
(8*9)+(7*5)+(6*5)+(5*0)+(4*2)+(3*8)+(2*8)+(1*3)=188
188 % 10 = 8
So 955028-83-8 is a valid CAS Registry Number.

955028-83-8SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name (3R,4R)-4-fluoropiperidin-3-ol,hydrochloride

1.2 Other means of identification

Product number -
Other names TRANS-4-FLUORO-3-PIPERIDINOL HYDROCHLORIDE

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:955028-83-8 SDS

955028-83-8Downstream Products

955028-83-8Relevant academic research and scientific papers

1 -OXO-1,2-DIHYDROISOQUINOLIN-7-YL-(5-SUBSTITUTED-THIOPHEN-2-YL)-SULFONAMIDE COMPOUNDS, FORMULATIONS CONTAINING THOSE COMPOUNDS, AND THEIR USE AS AICARFT INHIBITORS IN THE TREATMENT OF CANCERS

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Page/Page column 31-32, (2016/06/28)

1-Oxo-1,2-dihydroisoquinolin-7-yl-(5-substituted-thiophen-2-yl)-sulfonamide compounds, formulations containing those compounds, and their use as AICARFT inhibitors.

DIAZEPAM DERIVATIVES AS MODULATORS OF CHEMOKINE RECEPTORS

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Page/Page column 62, (2011/05/06)

The invention is concerned with novel bicyclic compounds of Formula (I), wherein n, m, p, A, L, R1, R2, R3, R4, R5, R6, R7, R7, R8, R9 and R10 are as defined in the description and in the claims, as well as physiologically acceptable salts thereof. These compounds are antagonists of CCR2 receptor, CCR5 receptor and/or CCR3 receptor and can be used as medicaments.

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