955030-40-7Relevant academic research and scientific papers
Total synthesis of fluvirucinine A1
Radha Krishna, Palakodety,Anitha, Kadimi
, p. 4546 - 4549 (2011/09/20)
An efficient and highly stereocontrolled convergent synthesis of fluvirucinine A1 is reported herein. In fluvirucinine A1 both C5-C13 and C1-C4 fragments were accessed from a common intermediate 6 derived from (S)-Roche ester in 15 and 7 steps, respectively. The key steps involve Evans asymmetric alkylation, Sharpless asymmetric epoxidation, amidation and a ring-closing metathesis reaction (RCM) for macrocyclization.
A cross-metathesis approach for the synthesis of tedanolide and 13-deoxytedanolide: stereoselective synthesis of the C3-C16 segment
Nyavanandi, Vijay Kumar,Nadipalli, Prabhakar,Nanduri, Srinivas,Naidu, Andra,Iqbal, Javed
, p. 6905 - 6911 (2008/02/13)
A unified synthetic strategy has been devised for the synthesis of both tedanolide and 13-deoxytedanolide, which involves a cross-metathesis reaction as the key step. We report herein the stereoselective synthesis of the C3-C16 segment (+)-5b and subseque
