95510-70-6

Basic information

• Product Name: Omeprazole sodium
• Synonyms: sodium 5-methoxy-2-[(4-methoxy-3,5-dimethyl-pyridin-2-yl)methylsulfinyl]benzoimidazole;OMEPRAZOLE SODIUM;5-methoxy-2-(((4-methoxy-3,5-dimethyl-2-pyridinyl)methyl)sulfinyl)-1h-benzimidazole sodium salt;Omeprazole powder/pellets/sodium;Omeprazole, sodium salt;odiuM 5-Methoxy-2-[(4-Methoxy-3,5-diMethyl-pyridin-2-yl)Methylsulfinyl]benzoiMidazole;1H-BenziMidazole, 6-Methoxy-2-[[(4-Methoxy-3,5-diMethyl-2-pyridinyl)Methyl]sulfinyl]-, sodiuM salt (1:1);omeprazole sodium:sodium 5-methoxy-2-((4-methoxy-3,5-dimethyl-pyridin-2-yl)methylsulfinyl)benzoIMIDAZOLE
• CAS NO: 95510-70-6
• Molecular Formula: C₁₇H₁₉N₃O₃S*Na
• Molecular Weight: 368.41
• EINECS: 1312995-182-4
• Product Categories: Active Pharmaceutical Ingredients;Omeprazole;Digestive System
• Mol File: 95510-70-6.mol

Chemical Properties

• Boiling Point: 600oC at 760mmHg
• Flash Point: 316.7oC
• Appearance: /
• Density: 1.37g/cm3
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• Solubility: Freely soluble in water and in ethanol (96 per cent), soluble in propylene glycol, very slightly soluble in methylene chloride.
• Stability: Hygroscopic
• CAS DataBase Reference: Omeprazole sodium(CAS DataBase Reference)
• NIST Chemistry Reference: Omeprazole sodium(95510-70-6)
• EPA Substance Registry System: Omeprazole sodium(95510-70-6)

Safety Data

• Hazardous Substances Data: 95510-70-6(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
Omeprazole sodium is used as an anti-ulcerative agent for the treatment of various gastric and duodenal ulcers, gastroesophageal reflux disease (GERD), and other conditions associated with excessive gastric acid production. It helps in reducing the acidity in the stomach, providing relief from heartburn, acid reflux, and other symptoms related to acid-related disorders.
Used in Gastroenterology:
In the field of gastroenterology, Omeprazole sodium is used to treat conditions such as Zollinger-Ellison syndrome, a rare disorder characterized by high levels of gastric acid production. It is also used in the eradication of Helicobacter pylori, a bacterium that can cause peptic ulcers and increase the risk of gastric cancer.
Used in Combination Therapy:
Omeprazole sodium is often used in combination with antibiotics and other medications for the treatment of H. pylori infections. This combination therapy helps in eradicating the bacteria and healing the ulcers more effectively.
Used in Long-term Management:
For individuals with a history of recurrent ulcers or GERD, Omeprazole sodium is used as a long-term management option to maintain remission and prevent the recurrence of symptoms.

InChI:InChI=1/C17H18N3O3S.Na/c1-10-8-18-15(11(2)16(10)23-4)9-24(21)17-19-13-6-5-12(22-3)7-14(13)20-17;/h5-8H,9H2,1-4H3;/q-1;+1

Relevant articles and documents

Omeprazole sodium salt

This invention relates to a novel form of the sodium salt of 5-methoxy-2-[[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfinyl]-1H-benzimidazole, known under the generic name omeprazole sodium salt. This invention also relates to processes for its preparation of omeprazole sodium form B which is thermodynamically stable, as well as pharmaceutical compositions containing it and its use in the treatment of gastrointestinal disorders.