955130-76-4Relevant academic research and scientific papers
Mechanism of methyl esterification of carboxylic acids by trimethylsilyldiazomethane
Kuehnel, Erik,Laffan, David D. P.,Lloyd-Jones, Guy C.,Martinez Del Campo, Teresa,Shepperson, Ian R.,Slaughter, Jennifer L.
, p. 7075 - 7078 (2007)
Minimal hazard: A deuterium-labeling study reveals that, contrary to prior assumption, the safe, reliable, and widely adopted method for methyl esterification of carboxylic acids using trimethylsilyldiazomethane (TMS-CHN2) proceeds through the concurrent acid-catalyzed methanolytic liberation of diazomethane (see scheme).
