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95522-45-5

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95522-45-5 Usage

Description

Colestimide was launched in Japan for the treatment of hyperlipidemia and hypercholesterolemia. It is a newly developed methyl imidazoleepichlorhydrin copolymer; this anion exchange resin works as a powerful bile acid sequestrant, thus increasing the rate of conversion of cholesterol to bile acids in the liver which may lead to enhancement of the rate of LDL removal. In animal models and humans, Colestimide proved to be more potent than cholestyramine and seems to be better tolerated. It reduced plasma levels of total and LDL cholesterol and did not alter HDL and triglyceride levels. Colestimide can be used in monotherapy or co-administered with HMG-CoA reductase inhibitors.

Uses

Colestilan, is a copolymer of 2-methyl-1H-imidazole and epichlorohydrin, and a bile acid sequestrans, that can be used for the treatment of hypercholesterolemia and dyslipidemia.

Brand name

Cholebine

Check Digit Verification of cas no

The CAS Registry Mumber 95522-45-5 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 9,5,5,2 and 2 respectively; the second part has 2 digits, 4 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 95522-45:
(7*9)+(6*5)+(5*5)+(4*2)+(3*2)+(2*4)+(1*5)=145
145 % 10 = 5
So 95522-45-5 is a valid CAS Registry Number.
InChI:InChI=1/C4H6N2.C3H5ClO/c1-4-5-2-3-6-4;4-1-3-2-5-3/h2-3H,1H3,(H,5,6);3H,1-2H2

95522-45-5SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name 2-(chloromethyl)oxirane,2-methyl-1H-imidazole

1.2 Other means of identification

Product number -
Other names Colestilan

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:95522-45-5 SDS

95522-45-5Upstream product

95522-45-5Downstream Products

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