955360-29-9

Usage

Structure

A piperidine derivative with a cyclobutyl group and an iodophenoxy group attached to the piperidine ring.

Potential applications

Medicinal chemistry, specifically in the development of pharmaceuticals targeting the central nervous system.

Presence of iodine and phenoxy groups

May impart specific properties, such as increased lipophilicity and potential for interactions with biological targets.

Further research and testing

Necessary to fully understand the pharmacological and toxicological properties of 1-cyclobutyl-4-(4-iodophenoxy)piperidine.

Upstream product

• 346617-98-9 1,1-dimethylethyl 4-[(4-iodophenyl)oxy]-1-piperidinecarboxylate 
• 352-34-1 4-fluoro-1-iodobenzene 
• 1191-95-3 cyclobutanone 
• 1220019-83-9 4-(4-iodophenoxy)piperidine hydrochloride 
• 955360-28-8 4-[(4-iodophenyl)oxy]piperidine trifluoroacetate 

Downstream Products

• 955360-30-2 4-{4-[(1-cyclobutyl-4-piperidinyl)oxy]phenyl}-3-butyn-1-ol 
• 1033055-13-8 1-cyclobutyl-4-[4-(4-nitro-1H-pyrazol-1-yl)phenoxy]piperidine 
• 955360-31-3 4-{4-[(1-cyclobutyl-4-piperidinyl)oxy]phenyl}-1-butanol 

Relevant academic research and scientific papers

MULTIPLE D2 A(NTA)GONISTS/H3 ANTAGONISTS FOR TREATMENT OF CNS-RELATED DISORDERS

The present invention relates to compounds compound according to Formula (III); and pharmaceutically acceptable salts, hydrates and solvates thereof. These compounds have D2receptor antagonist/(partial) agonist effects and H3antagonistic effects, pharmaceutical compositions thereof, and methods of using them for application in the prophylaxis or treatment of CNS disorders.

PYRAZOLE DERIVATIVE

A novel pyrazole derivative of the following formula having a histamine H3 receptor antagonistic effect: or a pharmaceutically acceptable salt thereof or a pharmaceutical preparation comprising the same as an active ingredient is effective for prevention

2-SUBSTITUTED 4-BENZYLPHTHALAZINONE DERIVATIVES AS HISTAMINE H1 AND H3 ANTAGONISTS

The present invention relates to compounds of formula (I), and salts thereof, processes for their preparation, to compositions containing them and to their use in the treatment of various disorders, such as allergic rhinitis.