95548-93-9

Basic information

• Product Name: 2-Propanol, 1-bromo-3-chloro-, acetate, (S)-
• CAS NO: 95548-93-9
• Molecular Formula: C5H8BrClO2
• Molecular Weight: 215.474
• Mol File: 95548-93-9.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 2-Propanol, 1-bromo-3-chloro-, acetate, (S)-(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Propanol, 1-bromo-3-chloro-, acetate, (S)-(95548-93-9)
• EPA Substance Registry System: 2-Propanol, 1-bromo-3-chloro-, acetate, (S)-(95548-93-9)

Safety Data

• Hazardous Substances Data: 95548-93-9(Hazardous Substances Data)

Upstream product

• 95589-30-3 (1S,2R,4R,4'R)-4'-Chloromethyl-4,7,7-trimethylbicyclo<2.2.1>heptane-2-spiro-2'-(1',3'-dioxolan)-3-one 

Downstream Products

• 84367-31-7 (R)-γ-chloro-β-hydroxybutyronitrile 
• 51594-55-9 (R)-(-)-epichlorohydrin 

Relevant articles and documents

Attempted Kinetic Resolution of 1,2-Diols by Camphorquinone: Generation of (R)-(Chloromethyl)oxirane

The epichlorohydrin (R)-(chloromethyl)oxirane has been prepared from rac-3-chloropropane-1,2-diol by means of the chiral ketone D-camphorquinone (1,7,7-trimethylbicycloheptane-2,3-dione).These reactions lead to intermediate dioxolanes which can be converted directly into oxiranes.This conversion was effected by reduction of the C-2-ketone of the dioxolane intermediate with sodium borohydride prior to reaction with hydrogen bromide-acetic acid followed by treatment of the resulting acetoxy bromide with sodium ethane-1,2-diolate.The diastereoselective formation of other dioxolanes was also investigated by reaction of D-camphorquinone with ethane-1,2-diol, propane-1,2-diol, and 3,3-dimethylbutane-1,2-diol.