95579-17-2

Basic information

• Product Name: Isoxazolo[4,5-c]pyridine, 4,5,6,7-tetrahydro-3-methoxy- (9CI)
• Synonyms: Isoxazolo[4,5-c]pyridine, 4,5,6,7-tetrahydro-3-methoxy- (9CI);3-methoxy-4,5,6,7-tetrahydroisoxazolo(4,5-c)pyridine
• CAS NO: 95579-17-2
• Molecular Formula: C₇H₁₀N₂O₂
• Molecular Weight: 154.1665
• Product Categories: OXAZOLE
• Mol File: 95579-17-2.mol

Chemical Properties

• Boiling Point: 325°Cat760mmHg
• Flash Point: 150.4°C
• Appearance: /
• Density: 1.165g/cm³
• Vapor Pressure: 0.000236mmHg at 25°C
• Refractive Index: 1.498
• CAS DataBase Reference: Isoxazolo[4,5-c]pyridine, 4,5,6,7-tetrahydro-3-methoxy- (9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: Isoxazolo[4,5-c]pyridine, 4,5,6,7-tetrahydro-3-methoxy- (9CI)(95579-17-2)
• EPA Substance Registry System: Isoxazolo[4,5-c]pyridine, 4,5,6,7-tetrahydro-3-methoxy- (9CI)(95579-17-2)

Safety Data

• Hazardous Substances Data: 95579-17-2(Hazardous Substances Data)

Usage

InChI:InChI=1/C7H10N2O2/c1-10-7-5-4-8-3-2-6(5)11-9-7/h8H,2-4H2,1H3

Upstream product

• 53601-98-2 methyl 3-hydroxy-4,5,6,7-tetrahydroisoxazolo<4,5-c>pyridine-5-carboxylate 
• 95628-20-9 methyl 2-methyl-3-oxo-2,3,6,7-tetrahydroisoxazolo[4,5-c]pyridine-5(4H)-carboxylate 
• 82988-64-5 methyl 3-methoxy-6,7-dihydroisoxazolo[4,5-c]pyridine-5(4H)-carboxylate 
• 101697-47-6 methyl 3-chloro-4,5,6,7-tetrahydroisoxazolo<4,5-c>pyridine-5-carboxylate 

Downstream Products

• 95597-20-9 5-Benzyl-3-methoxy-4,5,6,7-tetrahydro-isoxazolo[4,5-c]pyridine 
• 95579-22-9 3-Methoxy-5-methyl-4,5,6,7-tetrahydroisoxazolo[4,5-c]pyridine 

Relevant articles and documents

Design, synthesis, and pharmacological characterization of N - And O-substituted 5,6,7,8-tetrahydro-4H-isoxazolo[4,5-d]azepin-3-ol analogues: Novel 5-HT2A/5-HT2C receptor agonists with pro-cognitive properties

The isoxazol-3-one tautomer of the bicyclic isoxazole, 5,6,7,8-tetrahydro- 4H-isoxazolo[4,5-d]azepin-3-ol (THAZ), has previously been shown to be a weak GABAA and glycine receptor antagonist. In the present study, the potential in this scaffold

Tetrahydroisoxazolo[4,5-c]pyridine derivatives useful in the treatment of malfunctions of the acetylcholine or muscarinic systems

The present invention relates to novel compounds of the following formula: STR1 individual isomers and pharmaceutically acceptable acid addition salts thereof, wherein R1 is hydrogen, alkyl or phenyl-lower alkyl, in which the phenyl group may be substituted with halogen, lower alkyl or lower alkoxy; R2 is alkyl, alkenyl, alkynyl or phenyl-lower alkyl, in which the phenyl group may be substituted with halogen, lower alkyl or lower alkoxy; and R4 is hydrogen or alkyl. The invention moreover relates to methods for the preparation of the compounds of formula I, to novel intermediates, to pharmaceutical compositions containing same and to methods for the treatment of disorders, caused by malfunction of the acetylcholine (AcCh) or muscarinic system, by administering a non-toxic effective amount of a compound of the formula I.