955880-06-5Relevant academic research and scientific papers
Synthesis of pinacol arylboronates from aromatic amines: A metal-free transformation
Qiu, Di,Jin, Liang,Zheng, Zhitong,Meng, He,Mo, Fanyang,Wang, Xi,Zhang, Yan,Wang, Jianbo
, p. 1923 - 1933 (2013/03/29)
A metal-free borylation process based on Sandmeyer-type transformation using arylamines derivatives as the substrates has been developed. Through optimization of the reaction conditions, this novel conversion can be successfully applied to a wide range of aromatic amines, affording borylation products in moderate to good yields. Various functionalized arylboronates, which are difficult to access by other methods, can be easily obtained with this metal-free transformation. Moreover, this transformation can be followed by Suzuki-Miyaura cross-coupling without purification of the borylation products, which enhances the practical usefulness of this method. A possible reaction mechanism involving radical species has been proposed.
Efficient synthesis of biflavones having a ring-A ring of two flavone units using Suzuki cross-coupling reactions
Kohari, Yoshihito,Hoshino, Yukio,Matsuyama, Haruo,Nakano, Hiroto
scheme or table, p. 1871 - 1879 (2011/03/22)
Biflavones having a A ring-A ring of two flavone units were easily prepared by using Suzuki cross-coupling reaction of borylated flavones with bromoflavones or flavone-5-triflate in good to excellent yields. The Japan Institute of Heterocyclic Chemistry.
Inhibitory effect of synthetic C-C biflavones on various phospholipase A2s activity
Moon, Tae Chul,Quan, Zhejiu,Kim, Jeongsoo,Kim, Hyun Pyo,Kudo, Ichiro,Murakami, Makodo,Park, Haeil,Chang, Hyeun Wook
, p. 7138 - 7143 (2008/09/17)
Several prototypes of C-C biflavones (a-f) were synthesized and evaluated their inhibitory activity against phospholipase A2s (PLA2s) activity. The synthetic C-C biflavones (a-f) showed rather different inhibitory activity against va
