95598-73-5

Basic information

• Product Name: 9-(S)-(4-Benzoyloxy-2-tetrahydropyranyloxybutyl)adenine
• CAS NO: 95598-73-5
• Molecular Weight: 411.461
• Mol File: 95598-73-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 9-(S)-(4-Benzoyloxy-2-tetrahydropyranyloxybutyl)adenine(CAS DataBase Reference)
• NIST Chemistry Reference: 9-(S)-(4-Benzoyloxy-2-tetrahydropyranyloxybutyl)adenine(95598-73-5)
• EPA Substance Registry System: 9-(S)-(4-Benzoyloxy-2-tetrahydropyranyloxybutyl)adenine(95598-73-5)

Safety Data

• Hazardous Substances Data: 95598-73-5(Hazardous Substances Data)

Upstream product

• 95598-71-3 (S)-4-(2-benzoyloxy)ethyl-2,2-dimethyl-1,3-dioxolane 
• 95672-78-9 Benzoic acid (S)-3,4-dihydroxy-butyl ester 
• 613-90-1 benzoyl cyanide 
• 110-87-2 3,4-dihydro-2H-pyran 
• 95598-72-4 (2S)-4-O-Benzoyl-1-O-p-toluenesulfonylbutane-1,2,4-triol 
• 66224-66-6 adenine 

Relevant articles and documents

PREPARATION AND SYNTHETIC UTILIZATION OF 3-(ADENIN-9-YL)-2-HYDROXYALKANOIC ACIDS AND THEIR DERIVATIVES

Condensation of adenine and its substituted derivatives with 1,1-dialkoxy-2-bromoalkanes afforded substituted 2-(adenin-9-yl)-1,1-dialkoxyalkanes I and IV.Acid hydrolysis of I or IV, followed by reaction with alkali metal cyanides and acid hydrolysis, gave substituted 3-(adenin-9-yl)-2-hydroxyalkanoic acids II, V and VI.Methyl esters of these compounds (VIII) were converted into 3-(adenin-9-yl)alkane-1,2-diols IX by reduction with sodium borohydride. 3-(Adenin-9-yl)-2-methoxypropanoic acid (XVII) was obtained by oxidation of 9-(3-hydroxy-2-methoxypropyl)adenine (XVI)with sodium periodate; 4-(adenin-9-yl)-2-(S)-hydroxybutanoic acid (XXVII) was synthesized by oxidation of 9-(S)-(2-tetrahydropyranyloxy-4-hydroxybutyl)adenine (XXV), prepared from diethyl L-malate.Acid hydrolysis of XXV afforded 9-(S)-(2,4-dihydroxybutyl)adenine (XXVI). 4-(Adenin-9-yl)-3-hydroxypentanoic acid (XXIX) was obtained by reaction of malonic acid with 2-(adenin-9-yl)-1,1-diethoxypropane (IVa) in water.