955997-27-0Relevant academic research and scientific papers
BENZOFURAN AND BENZOTHIOPHENE DERIVATIVES USEFUL IN THE TREATMENT OF CANCERS OF THE CENTRAL NERVOUS SYSTEM
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Page/Page column 38-39, (2008/06/13)
The present invention relates to benzofuran and benzothiophene derivatives and compositions containing such compounds for the production of medicaments for the treatment of cancers of the central nervous system as monotherapy or combination with other agents.
BENZOFURAN DERIVATIVES USEFUL FOR TREATING HYPER-PROLIFERATIVE DISORDERS
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Page/Page column 94, (2008/06/13)
The invention relates to novel heterocycles of formula (I), processes for their preparation and their use for preparing medicaments for the treatment or prophylaxis of disorders, especially of hyperproliferative disorders.
TRICYCLIC FUROPYRIDINE DERIVATIVES USEFUL IN THE TREATMENT OF HYPER-PROLIFERATIVE DISORDERS
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Page/Page column 20, (2010/02/14)
This invention relates to a compound of Formula (I) Wherein X is CH2, 0 or N(C1-C3)alkyl; Ar1 is phenyl or pyridyl each optionally substituted with 1 or 2 substituents selected from (C1-C3)alkoxy, halo, OH, CF3, CN, NO2 and(C1-C3)alkyl, said alkyl being optionally substituted with CF3; or a pharmaceutically acceptable salt thereof, and its use in treating hyper-proliferative disorders.
FUROPYRIDINE AND FUROPYRIMIDINE DERIVATIVES FOR THE TREATMENT OF HYPER-PROLIFERATIVE DISORDERS
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Page 20, (2008/06/13)
This invention relates to a compound of Formula (I) wherein Y is CH or N; Ar1is phenyl or pyridyl each optionally substituted with 1 or 2 substituents each selected independently from (C1-C3)alkoxy halo, OH, CF3, CN, NO2 and (C1-C3)alkyl, said alkyl being optionally substituted with CF3; Ar2 is phenyl or pyridyl each optionally substituted with 1 or 2 substituents each independently selected from halo, OH, CN, NO2, CF3, (C1-C6)alkoxy, NR1R1, S(O)2R2, C(O)R3, and (C1-C6)alkyl optionally substituted with R4, and its use in treating hyper-proliferative disorders.
