956002-18-9Relevant academic research and scientific papers
Intramolecular Diels-Alder reactions of oxazole-olefins: synthesis of the Rauwolfia alkaloids suaveoline and norsuaveoline
Ohba, Masashi,Natsutani, Itaru,Sakuma, Takashi
, p. 10337 - 10344 (2007)
A full account of the highly stereoselective total synthesis of two indole alkaloids, suaveoline (4) and norsuaveoline (5), is presented. Central features of the synthetic strategy include the conversion of l-tryptophan methyl ester (12) into the oxazole
