95605-29-1

Upstream product

• 95605-32-6 [3-(3,4-Dichloro-phenyl)-3-oxo-propyl]-trimethyl-ammonium; bromide 
• 201230-82-2 carbon monoxide 
• 20555-91-3 3,4-dichloroiodobenzene 
• 1826-67-1 vinyl magnesium bromide 
• 6287-38-3 3,4-dichlorobenzaldehyde 
• 103058-93-1 3,4-Dichloro-α-ethenylbenzenmethanol 
• 1474048-88-8 1-(3,4-dichlorophenyl)-3-(phenylselanyl)propan-1-one 
• 75144-12-6 1-(3,4-dichlorophenyl)-3-dimethylamino-1-propanone hydrochloride 

Relevant academic research and scientific papers

Generation of α-Boryl Radicals and Their Conjugate Addition to Enones: Transition-Metal-Free Alkylation of gem-Diborylalkanes

A transition-metal-free method for the alkylation of gem-diborylalkanes with α,β-unsaturated ketones has been developed. It is demonstrated that the α-boryl radicals can be generated efficiently from gem-diborylalkanes with the aid of catechol and oxidants. The α-boryl radicals formed through such process can be engaged in conjugate addition reaction with α,β-unsaturated ketones. This transformation is a straightforward method for the synthesis of γ-borylketones.

KYNURENINE-3-MONOOXYGENASE INHIBITORS, PHARMACEUTICAL COMPOSITIONS, AND METHODS OF USE THEREOF

Certain compounds, or pharmaceutically acceptable salts or prodrugs thereof, pharmaceutical compositions comprising the same and methods of treating patients suffering from certain diseases and disorders responsive to the inhibition of KMO activity are de

Weinreb Amide based building block for convenient access to vinyl ketones

A new strategy for the synthesis of vinyl ketones has been achieved. Hitherto unknown and easily accessible, β-phenylseleno-N-methoxy-N- methylpropanamide, obtained through two simple reactions, served as a building block for convenient access to vinyl ketones. The N-methoxy-N-methyl amide moiety ensured no overaddition of the Grignard reagent and, hence, the excellent formation of β-phenylseleno ketones; oxidative work-up with hydrogen peroxide provided ready access to the vinyl ketones with concomitant loss of phenylselanol. Georg Thieme Verlag Stuttgart · New York.

Palladium-catalysed carbonylative cross-coupling reactions of aryl iodides and vinyl boron derivatives as a straightforward route to aryl vinyl ketones

The carbonylative cross-coupling of potassium vinyl trifluoroborate or 2,4,6-trivinyltricycloboroxane with aryl iodides under mild conditions affords aryl vinyl ketones. The optimisation of the reaction conditions leads to the targeted enones in good yiel