956102-59-3

Basic information

• Product Name: S-2-ISOPROPYL-2-METHYL-1-(TOLUENE-4-SULFONYL)-AZIRIDINE
• Synonyms: S-2-ISOPROPYL-2-METHYL-1-(TOLUENE-4-SULFONYL)-AZIRIDINE
• CAS NO: 956102-59-3
• Molecular Formula: C₁₃H₁₉NO₂S
• Molecular Weight: 253.36
• Mol File: 956102-59-3.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 349.5±35.0 °C(Predicted)
• Appearance: /
• Density: 1.160±0.06 g/cm3(Predicted)
• PKA: -6.46±0.40(Predicted)
• CAS DataBase Reference: S-2-ISOPROPYL-2-METHYL-1-(TOLUENE-4-SULFONYL)-AZIRIDINE(CAS DataBase Reference)
• NIST Chemistry Reference: S-2-ISOPROPYL-2-METHYL-1-(TOLUENE-4-SULFONYL)-AZIRIDINE(956102-59-3)
• EPA Substance Registry System: S-2-ISOPROPYL-2-METHYL-1-(TOLUENE-4-SULFONYL)-AZIRIDINE(956102-59-3)

Safety Data

• Hazardous Substances Data: 956102-59-3(Hazardous Substances Data)

Upstream product

• 4378-19-2 (S)-α-Methylvaline 
• 956102-64-0 methylvalinol 
• 98-59-9 p-toluenesulfonyl chloride 

Downstream Products

• 956102-61-7 benzyl (1S,4aR,6aS,7R,8R,10aR,10bR,12aR,14R,15R)-15-[[(2S)-2,3-dimethyl-2-[[(4-methylphenyl)sulfonyl]amino]butyl]oxy]-8-[(1R)-1,2-dimethylpropyl]-14-methoxy-1,6,6a,7,8,9,10,10a,10b,11,12,12a-dodecahydro-1,6a,8,10a-tetramethyl-4H-1,4a-propano-2H-phenanthro[1,2-c]pyran-7-carboxylate 

Relevant articles and documents

ANTIFUNGAL AGENTS

Novel derivatives of enfumafungin are disclosed herein, along with their pharmaceutically acceptable salts, hydrates and prodrugs. Also disclosed are compositions comprising such compounds, methods of preparing such compounds and methods of using such compounds as antifungal agents and/or inhibitors of (l,3)-β-D-glucan synthase. The disclosed compounds, their pharmaceutically acceptable salts, hydrates and prodrugs,,as well as compositions comprising such compounds, salts, hydrates and prodrugs, are useful for treating and/or preventing fungal infections and associated diseases and conditions.

ANTIFUNGAL AGENTS

The present invention relates to novel enfumafungin derivatives of Formula IV-IA and pharmaceutically acceptable salts thereof, their synthesis, and their use as inhibitorspf(r,3)-β-D-glucan synthase. The present compounds and pharmaceutically acceptable salts therp?τ, as WeILaS1Sy-pharmaceutical compositions comprising the present compounds and pharmaceuticalty acceptable salts thereof, are useful for treating or preventing antifungal infections and associated diseases and conditions.