956242-57-2

Basic information

• Product Name: (S)-1-((tert-butyldiphenylsilyl)oxy)-3-methyloctan-4-one
• Synonyms: (S)-1-((tert-butyldiphenylsilyl)oxy)-3-methyloctan-4-one
• CAS NO: 956242-57-2
• Molecular Weight: 396.645
• Mol File: 956242-57-2.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: (S)-1-((tert-butyldiphenylsilyl)oxy)-3-methyloctan-4-one(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-1-((tert-butyldiphenylsilyl)oxy)-3-methyloctan-4-one(956242-57-2)
• EPA Substance Registry System: (S)-1-((tert-butyldiphenylsilyl)oxy)-3-methyloctan-4-one(956242-57-2)

Safety Data

• Hazardous Substances Data: 956242-57-2(Hazardous Substances Data)

Upstream product

• 693-02-7 hex-1-yne 
• 87682-13-1 (+)-(R)-2-methyl-4-nonyn-3-ol 
• 187458-29-3 (2S, 3S)-5-(tert-butyldiphenylsilyloxy)-3-methylpentane-1,2-diol 
• 169387-99-9 (S)-2-methyl-4-(tert-butyldiphenylsilyloxy)butanol 
• 58479-61-1 tert-butylchlorodiphenylsilane 
• 70423-38-0 (S)-2-methyl-1,4-butandiol 

Relevant articles and documents

Hydroxy-Directed Ruthenium-Catalyzed Alkene/Alkyne Coupling: Increased Scope, Stereochemical Implications, and Mechanistic Rationale

The recognition of the dual binding mode of propargyl and allyl alcohols to [Cp*Ru] fragments fostered the development of a highly regioselective intermolecular Alder-ene-type reaction of alkynes with 1,2-disubstituted alkenes. The increased substrate scope opens new perspectives in stereochemical terms. As the loaded catalyst is chiral-at-metal, stereochemical information is efficiently relayed from the propargylic site to the emerging C?C bond. This interpretation is based on the X-ray structure of the first Cp*Ru complex carrying an intact enyne ligand, and provides valuable insights into bonding and activation of the substrates. Computational data draw a clear picture of the principles governing regio- and stereocontrol.