956461-79-3

Basic information

• Product Name: 8-Chloro-2,3,4,5-tetrahydropyrido[3,2-f][1,4]oxazepine
• Synonyms: 8-chloro-2,3,4,5-tetrahydropyrido[3,2-f][1,4]oxazepine
• CAS NO: 956461-79-3
• Molecular Formula: C8H9ClN2O
• Molecular Weight: 184.62
• Mol File: 956461-79-3.mol
• Article Data: 0

Chemical Properties

• Boiling Point: 317.8 °C at 760 mmHg
• Flash Point: 146 °C
• Appearance: /
• Density: 1.262 g/cm³
• Refractive Index: 1.546
• CAS DataBase Reference: 8-Chloro-2,3,4,5-tetrahydropyrido[3,2-f][1,4]oxazepine(CAS DataBase Reference)
• NIST Chemistry Reference: 8-Chloro-2,3,4,5-tetrahydropyrido[3,2-f][1,4]oxazepine(956461-79-3)
• EPA Substance Registry System: 8-Chloro-2,3,4,5-tetrahydropyrido[3,2-f][1,4]oxazepine(956461-79-3)

Safety Data

• Hazardous Substances Data: 956461-79-3(Hazardous Substances Data)

Usage

General Description

8-Chloro-2,3,4,5-tetrahydropyrido[3,2-f][1,4]oxazepine, also known as "clozapine," is a synthetic tricyclic compound with antipsychotic properties. It acts as a serotonin and dopamine receptor antagonist, and is used in the treatment of schizophrenia, particularly in patients who do not respond to other antipsychotic medications. Clozapine has also been found to be effective in reducing suicidal behavior in patients with schizophrenia and other psychiatric disorders. However, it also carries a risk of potentially serious side effects, including agranulocytosis, myocarditis, and seizures, and therefore requires close monitoring of blood cell counts and cardiovascular function in patients undergoing treatment. Despite these risks, clozapine remains a valuable option for the management of treatment-resistant schizophrenia.

InChI:InChI=1/C8H9ClN2O/c9-7-2-1-6-5-10-3-4-12-8(6)11-7/h1-2,10H,3-5H2