95650-58-1

Upstream product

• 14235-81-5 4-Ethynylaniline 
• 407-25-0 trifluoroacetic anhydride 

Downstream Products

• 1425510-15-1 N-(4-((2,6-bis(bromomethyl)pyridin-4-yl)ethynyl)phenyl)-2,2,2-trifluoroacetamide 
• 1425510-16-2 diethyl 6,6'-((((4-((4-trifluoroacetamidophenyl)ethynyl)-pyridine-2,6-diyl)bis(methylene))bis((2-ethoxy-2-oxoethyl)azanediyl))bis(methylene))-bis(4-bromopicolinate) 
• 1425510-14-0 N-(4-((2,6-bis(hydroxymethyl)pyridin-4-yl)ethynyl)phenyl)-2,2,2-trifluoroacetamide 

Relevant academic research and scientific papers

Design of novel, water soluble and highly luminescent europium labels with potential to enhance immunoassay sensitivities

To meet the continual demands of more-sensitive immunoassays, the synthesis of novel luminescent Eu(III) chelate labels having similar substituted 4-(phenylethynyl)pyridine chromophores in three different chelate structure classes are reported. Significan

LUMINESCENT TRIAZACYCLONONANE-BASED LANTHANIDE CHELATE COMPLEXES AS LABELLING REAGENTS

The invention relates to a detectable molecule comprising a biospecific binding reactant attached to a macrocyclic luminescent lanthanide chelate comprising a lanthanide ion and a chelating ligand of the formula (I) wherein, R1 consists of a li

NOVEL LUMINESCENT LANTHANIDE CHELATES WITH ENHANCED EXCITATION PROPERTIES

The present application discloses a luminescent lanthanide chelate comprising one or more chromophoric moieties of the formula (I) or of the formula (III) wherein R1, R2 and R2* each independently are selected from carbon-containing substituents forming a C—O bond with the neighbouring oxygen atom, R3 and R4 each represent a bond between the chromophoric moiety and other moieties of the chelate, and Ln3+ is a lanthanide ion, as well as the corresponding luminescence lanthanide chelating ligand. The application also discloses a detectable molecule comprising a biospecific binding reactant (such as an antibody) conjugated to the luminescent lanthanide chelate as well as a method of carrying out a biospecific binding assay, the use of such a detectable molecule in a specific bioaffinity based binding assay utilizing time-resolved fluorometric determination of a specific luminescence, and a solid support material conjugated with the luminescent lanthanide chelate.

Arylsulfonamidobenzylic compounds

Arylsulfonamidobenzyl alcohols, amines and sulfonamides are provided which are useful in treating lipid disorders, metabolic diseases and cell-proliferative diseases.