956513-06-7Relevant academic research and scientific papers
Synthesis and antiviral properties of aza-analogues of ganciclovir derived from 5,5-bis(hydroxymethyl)pyrrolidin-2-one
Koszytkowska-Stawińska, Mariola,Ko?aczkowska, Ewa,Adamkiewicz, Ewa,De Clercq, Erik
, p. 10587 - 10595 (2008/02/13)
Novel aza-analogues of ganciclovir were obtained from 1,5,5-tris(pivaloyloxymethyl)pyrrolidin-2-one by a one-pot base silylation/nucleoside coupling procedure. The compounds were evaluated for, but found to be devoid of, antiviral activity in vitro.
