956580-34-0

Basic information

• Product Name: ((2-bromo-5-methoxybenzyl)oxy)triisopropylsilane
• Synonyms: ((2-bromo-5-methoxybenzyl)oxy)triisopropylsilane
• CAS NO: 956580-34-0
• Molecular Weight: 373.406
• Mol File: 956580-34-0.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: ((2-bromo-5-methoxybenzyl)oxy)triisopropylsilane(CAS DataBase Reference)
• NIST Chemistry Reference: ((2-bromo-5-methoxybenzyl)oxy)triisopropylsilane(956580-34-0)
• EPA Substance Registry System: ((2-bromo-5-methoxybenzyl)oxy)triisopropylsilane(956580-34-0)

Safety Data

• Hazardous Substances Data: 956580-34-0(Hazardous Substances Data)

Upstream product

• 13154-24-0 triisopropylsilyl chloride 
• 150192-39-5 2-Bromo-5-methoxybenzyl alcohol 

Relevant articles and documents

Synthesis of Tetrahydroisoquinolines through an Iron-Catalyzed Cascade: Tandem Alcohol Substitution and Hydroamination

Rapid assembly of saturated nitrogen heterocycles - the synthetically more challenging variants of their aromatic relatives - can expedite the synthesis of biologically relevant molecules. Starting from a benzylic alcohol tethered to an unactivated alkene, an iron-catalyzed tandem alcohol substitution and hydroamination provides access to tetrahydroisoquinolines in a single synthetic step. Using a mild iron-based catalyst, the combination of these operations forms two carbon-nitrogen bonds and provides a unique annulation strategy to access this valuable core.

PENTACYCLIC INDOLE DERIVATIVES AS ANTIVIRAL AGENTS

The present invention relates to pentacyclic indole derivatives of formula (I): wherein A, Ar, R1, R2, W, X, Y and Z are defined herein, and pharmaceutically acceptable salts thereof, pharmaceutical compositions comprising them, and their use for the treatment or prevention of infection by hepatitis C virus.