956593-14-9

Usage

Uses

Used in Pharmaceutical Industry:
1-(3-Methylphenyl)-5-oxopyrrolidine-3-carbohydrazide is used as a therapeutic agent for the treatment of type 2 diabetes. Its application is based on its ability to inhibit the DPP-4 enzyme, which plays a role in regulating blood sugar levels. By inhibiting this enzyme, it may help improve glycemic control and provide a potential treatment option for patients with type 2 diabetes.
Additionally, due to its potential therapeutic effects on other metabolic disorders, 1-(3-Methylphenyl)-5-oxopyrrolidine-3-carbohydrazide may be used as a research compound for the development of new drugs targeting metabolic conditions. Its application in this context is driven by the need for novel treatments to address the growing prevalence of metabolic disorders worldwide.

Upstream product

• 1071346-78-5 C₁₃H₁₅NO₃ 

Downstream Products

• 956593-16-1 C₁₅H₁₉N₃O₂ 
• 956593-19-4 C₁₇H₁₉N₃O₂ 
• 1342800-39-8 N'-(3-chloro-1,4-dioxo-1,4-dihydronaphthalen-2-yl)-1-(3-methylphenyl)-5-oxopyrrolidine-3-carbohydrazide 
• 1342800-28-5 N'-(3-methyl-4-oxo-1,4-dihydronaphthalen-1-ylidene)-1-(3-methylphenyl)-5-oxopyrrolidine-3-carbohydrazide 
• 1342800-21-8 1-(3-methylphenyl)-5-oxo-N'-(4-oxo-1,4-dihydronaphthalen-1-ylidene)pyrrolidine-3-carbohydrazide 

Relevant academic research and scientific papers

Reactions of 5-oxo-1-phenylpyrrolidine-3-carbohydrazides with 1,4-naphthoquinone derivatives and the properties of the obtained products

N′-(4-Oxo-1,4-dihydronaphthalen-1-ylidene)-1-phenyl-5-oxopyrrolidine- 3-carbohydrazides and N′-(3-methyl-4-oxo-1,4-dihydronaphthalen-1-ylidene)- 1-phenyl-5-oxopyrrolidine-3-carbohydrazides were synthesized by reactions of 5-oxo-1-phenylpyrrolidine-3-carbo

Synthesis and investigation of some 1,4-disubstituted 2-pyrrolidinones

A series of condensation products of 1-aryl-4-hydrazinecarbonyl-2- pyrrolidinones with acetone, 2,4-pentanedione, and aromatic aldehydes was obtained and identified by the combination of IR, mass and 1H, 13C NMR spectroscopy. The results of their structural studies by NMR spectroscopy are provided. It was ascertained that the presence of the NH group determines the existence of the mixtures of the Z/E-isomers of compounds under study. The availability of Z-isomer as a sterically favorable one was also verified by computer molecular modeling. Springer Science+Business Media, Inc. 2006.