95669-16-2Relevant academic research and scientific papers
2-Azabicyclo(2.2.2)octane derivatives and their use as immunosuppressive agents
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, (2008/06/13)
The invention relates to new 2-azabicyclo[2.2.2]octane derivatives of the formula (I), STR1 wherein A is hydrogen, alkoxycarbonyl having from one to 4 carbon atoms in the alkoxy group, phenylalkoxycarbonyl having from one to 4 carbon atoms in the alkoxy moiety, alkyl having from one to 6 carbon atoms, aralkyl containing from one to 4 carbon atoms in the alkyl moiety or substituted acyl, R1 is hydrogen or alkyl having from one to 4 carbon atoms, Z is hydrogen or halogen, X is hydrogen or halogen, Y is hydrogen, or X and Y together represent a C--C bond, W is alkoxycarbonyl having from one to 4 carbon atoms in the alkoxy moiety, cyano, carboxamido or haloformyl, or if X stands for halogen, X and Y together represent a STR2 group. According to another aspect of the invention there is provided a process for the preparation of the above compounds, which are pharmaceutically active, in particular, possess valuable anticonvulsive, vasodilating or gastric acid secretion inhibiting properties. Pharmaceutical compositions containing compounds of the formula (I) are also within the scope of the invention.
Indolo[2,3-a]quinolizine and indolo[2,3-g]cyclopent[a]indolizine derivatives, compositions and methods employing them for treating ulcers
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, (2008/06/13)
The invention relates to new indolo[2,3-g]cyclopent[a]indolizine derivatives of the formulae (II) STR1 and/or (III) STR2 wherein W is alkoxycarbonyl having from one to four carbon atoms in the alkoxy moiety or cyano, R1 is hydrogen or alkyl hav
