956897-67-9Relevant academic research and scientific papers
Copper-catalyzed arylation of heterocycle C-H bonds
Do, Hien-Quang,Daugulis, Olafs
, p. 12404 - 12405 (2008/09/17)
A new method for the direct, copper-catalyzed arylation of heterocycle C-H bonds by aryl halides has been developed. In addition to electron-rich five-membered heterocycles, electron-poor pyridine oxides can also be arylated. The best results are obtained by using a combination of lithium tert-butoxide base, aryl iodide coupling partner, and copper iodide catalyst. Copyright
