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PF 04217903 mesylate is a high affinity and highly selective c-Met inhibitor, with a Ki value of 6-7 nM against the wild type c-Met. It demonstrates a remarkable selectivity of over 1000-fold for c-Met compared to a panel of 208 kinases.

956906-93-7

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956906-93-7 Usage

Uses

Used in Pharmaceutical Industry:
PF 04217903 mesylate is used as a c-Met inhibitor for targeting the c-Met receptor, which plays a crucial role in various cellular processes, including cell proliferation, migration, and survival. Its high selectivity and affinity make it a promising candidate for the development of targeted therapies against cancer and other diseases where the c-Met pathway is dysregulated.
Used in Cancer Research:
PF 04217903 mesylate is used as a research tool in cancer research to study the role of c-Met in tumor growth, invasion, and metastasis. Its high selectivity allows researchers to specifically target the c-Met pathway, providing valuable insights into the development of novel therapeutic strategies for cancer treatment.
Used in Drug Development:
PF 04217903 mesylate is used in drug development as a lead compound for the design and synthesis of new c-Met inhibitors. Its high affinity and selectivity serve as a benchmark for the development of more potent and specific inhibitors, potentially leading to the discovery of new drugs for the treatment of c-Met-dependent diseases.

Check Digit Verification of cas no

The CAS Registry Mumber 956906-93-7 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 9,5,6,9,0 and 6 respectively; the second part has 2 digits, 9 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 956906-93:
(8*9)+(7*5)+(6*6)+(5*9)+(4*0)+(3*6)+(2*9)+(1*3)=227
227 % 10 = 7
So 956906-93-7 is a valid CAS Registry Number.

956906-93-7 Well-known Company Product Price

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  • Sigma

  • (SML0263)  PF-04217903  ≥98% (HPLC)

  • 956906-93-7

  • SML0263-5MG

  • 1,301.04CNY

  • Detail

  • Sigma

  • (SML0263)  PF-04217903  ≥98% (HPLC)

  • 956906-93-7

  • SML0263-25MG

  • 5,253.30CNY

  • Detail

956906-93-7SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name methanesulfonic acid,2-[4-[3-(quinolin-6-ylmethyl)triazolo[4,5-b]pyrazin-5-yl]pyrazol-1-yl]ethanol

1.2 Other means of identification

Product number -
Other names UNII-149X53W31J

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:956906-93-7 SDS

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