95697-80-6Relevant academic research and scientific papers
An environmentally benign synthesis of aurones and flavones from 2′-acetoxychalcones using n-tetrabutylammonium tribromide
Bose, Gopal,Mondal, Ejabul,Khan, Abu T,Bordoloi, Manob J.
, p. 8907 - 8909 (2007/10/03)
A wide variety of aurones (3a-f) can be prepared exclusively from 2′-acetoxychalcones (1a-f) in high yields in two steps, by bromination using n-tetrabutylammonium tribromide (TBATB) in the presence of CaCO3 in CH2Cl2-MeOH (5:2) at 0-5°C followed by cyclization of the brominated products 2a-f on treating with 0.2 M ethanolic KOH solution at 0-5°C, respectively. In contrast various flavone derivatives 6a-f can be obtained exclusively from compounds 1a-f in fairly good yields, by brominating with the same reagent in CH2Cl2, followed by dehydrobromination and finally cyclization on treating with 0.1 M NaOMe solution.
