95698-08-1Relevant academic research and scientific papers
Suzuki arylation of 1,1-Dibromo-1-alkenes: Synthesis of tetra-substituted alkenes
Bauer,Miller,Vice,McCombie
, p. 254 - 256 (2001)
1,1-Dibromo-1-alkenes were coupled with a variety of aryl boronic acids using Suzuki conditions (PdCl2(PPh3)2/Na2CO3/T HF-H2O or DME-H2O/65-90 °C). The 1,1-dibromo-1-alkenes were prepared from ketones, and thus, the overall process furnished tetra-substituted alkenes in a very efficient manner.
