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N-t-Butyl-N-(4-methoxybenzyl) 4-boronobenzenesulfonamide, commonly known as Bortezomib, is a potent chemical compound that functions as a proteasome inhibitor. It is primarily used in the treatment of multiple myeloma and mantle cell lymphoma, where it disrupts the protein degradation process in cancer cells, thereby inducing cell death. Bortezomib is a significant component of modern chemotherapy protocols for these cancers, demonstrating substantial efficacy in enhancing patient outcomes.

957060-86-5

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957060-86-5 Usage

Uses

Used in Oncology:
Bortezomib is utilized as an anticancer agent for the treatment of multiple myeloma and mantle cell lymphoma. It acts as a proteasome inhibitor, interfering with the normal function of protein degradation in cancer cells, which leads to their death. This mechanism of action makes Bortezomib a crucial part of chemotherapy regimens for these types of cancer, significantly improving patient outcomes.
However, the use of Bortezomib can also result in side effects such as peripheral neuropathy, thrombocytopenia, and gastrointestinal disturbances. To mitigate these side effects and enhance the therapeutic efficacy of Bortezomib, it is typically administered as an intravenous or subcutaneous injection and is often used in combination with other chemotherapy drugs. This approach allows for a more effective treatment strategy while managing potential side effects.

Check Digit Verification of cas no

The CAS Registry Mumber 957060-86-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 9,5,7,0,6 and 0 respectively; the second part has 2 digits, 8 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 957060-86:
(8*9)+(7*5)+(6*7)+(5*0)+(4*6)+(3*0)+(2*8)+(1*6)=195
195 % 10 = 5
So 957060-86-5 is a valid CAS Registry Number.

957060-86-5 Well-known Company Product Price

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  • Alfa Aesar

  • (H52944)  4-[tert-Butyl(4-methoxybenzyl)sulfamoyl]benzeneboronic acid, 98%   

  • 957060-86-5

  • 250mg

  • 1194.0CNY

  • Detail

  • Alfa Aesar

  • (H52944)  4-[tert-Butyl(4-methoxybenzyl)sulfamoyl]benzeneboronic acid, 98%   

  • 957060-86-5

  • 1g

  • 3822.0CNY

  • Detail

957060-86-5SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 20, 2017

Revision Date: Aug 20, 2017

1.Identification

1.1 GHS Product identifier

Product name (4-(N-(tert-Butyl)-N-(4-methoxybenzyl)sulfamoyl)phenyl)boronic acid

1.2 Other means of identification

Product number -
Other names [4-[tert-butyl-[(4-methoxyphenyl)methyl]sulfamoyl]phenyl]boronic acid

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:957060-86-5 SDS

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