957211-48-2

Upstream product

• 957211-36-8 3-(2,6-dibromo-phenyl)-propionic acid ethyl ester 
• 70126-45-3 3-(1,1,2,2-tetrafluoro-ethoxy)-benzoic acid methyl ester 

Downstream Products

• 957211-40-4 3-(2,6-dibromo-phenyl)-1-[3-(1,1,2,2-tetrafluoroethoxy)-phenyl]-propan-1-one 

Relevant academic research and scientific papers

Improved asymmetric synthesis of 3,4-dihydro-2-[3-(1,1,2,2- tetrafluoroethoxy)phenyl]-5-[3-(trifluoromethoxy)phenyl]-α- (trifluoromethyl)-1(2H)-quinolineethanol, a potent cholesteryl ester transfer protein inhibitor

The asymmetric synthesis of 3,4-dihydro-2-[3-(1,1,2,2-tetrafluoroethoxy) phenyl]-5-[3-(trifluoromethoxy)phenyl]-α-(trifluoromethyl)-1(2H) -quinolineethanol (compound 11), a cholesteryl ester transfer protein inhibitor, Is accomplished. The asymmetric cent

1,2,3,4-TETRAHYDRO-QUINOLINE DERIVATIVES AS CETP INHIBITORS

The invention is directed to compounds of Formula (I) described herein useful as CETP inhibitors, compositions containing them, and methods of using them.