957217-04-8

Basic information

• Product Name: 2-(4-chlorophenyl)-3-(2-pyridyl)-4(3H)-quinazolinone
• CAS NO: 957217-04-8
• Molecular Weight: 333.777
• Mol File: 957217-04-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2-(4-chlorophenyl)-3-(2-pyridyl)-4(3H)-quinazolinone(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(4-chlorophenyl)-3-(2-pyridyl)-4(3H)-quinazolinone(957217-04-8)
• EPA Substance Registry System: 2-(4-chlorophenyl)-3-(2-pyridyl)-4(3H)-quinazolinone(957217-04-8)

Safety Data

• Hazardous Substances Data: 957217-04-8(Hazardous Substances Data)

Upstream product

• 504-29-0 2-aminopyridine 
• 18600-52-7 2-(4-chlorophenyl)-4H-benzo[d][1,3]oxazin-4-one 

Relevant articles and documents

Synthesis and anti-inflammatory activity of 2,3-diaryl-4(3H)-quinazolinones

2,3-Diaryl-4(3H)-quinazolinones containing various substituents on diaryl rings have been synthesized and evaluated for their cyclooxygenase-2 inhibitory activity by the colorimetric COX (ovine) inhibitor screening assay and anti-inflammatory activity by the carrageenan-induced rat paw edema assay. 2-(4-Nitrophenyl)-3-(4-tolyl)-4(3H)-quinazolinone showed a maximum COX-2 inhibition of 27.72% at 22 μM concentration in the present series and exhibited a mild anti-inflammatory activity at a dose of 50 mg/kg in carrageenan-induced rat paw edema assay.