95741-07-4Relevant academic research and scientific papers
INFLUENCE OF ENOLATE GEOMETRY ON THE STEREOCHEMISTRY OF MICHAEL ADDITIONS OF KETONE ENOLATES TO α, β-UNSATURATED KETONES
Oare, David A.,Heathcock, Clayton H.
, p. 6169 - 6172 (2007/10/02)
Preformed lithium enolates of ketones react with acyclic α,β-unsaturated ketones to give 1,5-diketones in good chemical yields.A strong correlation exists between enolate geometry and product stereochemistry; enolates having the Z configuration provide anti addition products while E enolates usually provide the syn diastereomers.
