95758-07-9Relevant academic research and scientific papers
Syntheses of 2,6,9-Trisubstituted Purines and Their Antiviral Activity
Bhakuni, D. S.,Gupta, P. K.,Chowdhury, B. L.
, p. 1286 - 1288 (2007/10/02)
2-Chloro- and 2-alkoxy-6-aminoalkyl-9-(2-tetrahydropyranyl)-9H-purines (3-14), 2-alkylthio-9-(tetrahydropyranyl) adenines (15-17), and 2-alkylthio-9-tetrahydropyranyl-8-azaadenines (18-20) have been synthesized.Compounds (2 to 14) have been screened against Ranikhet disease virus.Of the compounds tested 2, 3, 11 and 13 exhibit above 75percent inhibition against RDV.
