95770-22-2Relevant academic research and scientific papers
A stimuli-responsive insulin delivery system based on reversible phenylboronate modified cyclodextrin with glucose triggered host-guest interaction
Xu, Xinyuan,Shang, Hui,Zhang, Tianyu,Shu, Panjing,Liu, Yanpeng,Xie, Jing,Zhang, Dongyue,Tan, Hong,Li, Jianshu
, p. 649 - 658 (2018)
Injection of insulin is an effective therapy to treat most patients with the type I diabetes and some with type II diabetes. Additionally, the release of insulin under specific conditions has attracted widespread interest. In this study, a smart drug carr
Intelligent insulin delivery system with good salt tolerance and preparation process
-
Paragraph 0032; 0063, (2017/08/28)
The invention discloses an intelligent insulin delivery system with good salt tolerance and a preparation process, and belongs to the field of bio-materials. Amphiphilic mPEG-b-PBLG and mPEG-b-PPBDEMA are self-assembled to obtain a composite nano-drug carrier; the composite nano-drug carrier wraps insulin to form an insulin-wrapped composite nanoparticle drug delivery system; a structure formula of mPEG-b-PBLG is shown in the specification; and a structure formula of mPEG-b-PPBDEMA is shown in P-2 or P-3 of the specification.
A facile strategy for polymers to achieve glucose-responsive behavior at neutral pH
Yao, Yuan,Wang, Xuemin,Tan, Tianwei,Yang, Jing
scheme or table, p. 7948 - 7951 (2012/03/12)
A novel type of amphiphilic block polymer with phenylboronate ester as a leaving group in the hydrophobic block was designed and synthesized as a nanocarrier to successfully realize glucose-responsiveness at neutral pH.
Cyclic triolborates: Air- and water-stable ate complexes of organoboronic acids
Yamamoto, Yasunori,Takizawa, Miho,Yu, Xiao-Qiang,Miyaura, Norio
, p. 928 - 931 (2008/09/20)
(Chemical Equation Presented) A borate in the hand is a convenient reagent for palladium- and copper-catalyzed C-C and C-N bond-forming reactions, especially when, like the title bench-stable complexes, it demonstrates high transmetalation efficiency. Cyclic triolborates can be synthesized readily from organoboronic acids (see scheme), can be handled and stored without special precautions, and are relatively soluble in organic solvents.
