957770-67-1Relevant articles and documents
Total synthesis of (-)-nakadomarin A
Kyle, Andrew F.,Jakubec, Pavol,Cockfield, Dane M.,Cleator, Ed,Skidmore, John,Dixon, Darren J.
, p. 10037 - 10039 (2011)
A highly diastereoselective bifunctional organocatalyst controlled Michael addition, a nitro-Mannich/lactamization cascade, a furan N-acyliminium cyclisation, a sequential alkyne RCM/syn-reduction and an alkene RCM has allowed a 19 step, highly stereosele
Asymmetric indoline synthesis via intramolecular aza-Michael addition mediated by bifunctional organocatalysts
Miyaji, Ryota,Asano, Keisuke,Matsubara, Seijiro
, p. 3658 - 3661 (2013/08/23)
A novel method for the asymmetric synthesis of 2-substituted indolines, employing bifunctional amino(thio)urea catalysts, was developed. The reaction proceeded via an intramolecular aza-Michael addition mediated by activation through hydrogen bonding. The