957828-79-4Relevant articles and documents
A general approach to the synthesis of substituted isoxazolo[4,3-c] quinolines via chalcones
Madapa, Sudharshan,Sridhar, Divya,Yadav, Gaya P.,Maulik, Prakas R.,Batra, Sanjay
, p. 4343 - 4351 (2008/04/13)
A general and practical approach to the synthesis of substituted isoxazolo[4,3-c]quinolines from the substituted isoxazolines obtained by 1,3-dipolar cycloadditions between 2-nitrobenzonitrile oxide and chalcones is described. SnCl2·2H2O-mediated reduction of the nitro group, followed by intramolecular cyclization involving the amino and the keto groups in these substrates, furnished mixtures of isoxazolo[4,3-c] quinolines and 3,5-dihydroisoxazolo[4,3-c]-quinolines. In contrast, the reduction of these substrates with Fe/AcOH unexpectedly yielded 3-benzoylquinolin-4-yl-amine derivatives. Wiley-VCH Verlag GmbH & Co. KGaA, 2007.